TheBrief.Health

Study shows patients with chronic conditions face higher out-of-pocket costs for preventive care despite ACA protections, highlighting billing issues and need for standardized cost-sharing practices.

Study shows adults with metastatic colorectal cancer have worse survival in low socioeconomic neighborhoods and among Black patients, highlighting structural inequities and need for interventions.

California will end Medicaid coverage for GLP-1 weight loss drugs in 2026, limiting obesity treatment access for low-income residents despite effectiveness and affordability concerns.

Pathological Demand Avoidance involves extreme demand avoidance, often overlapping autism, frequently underrecognized, requiring early identification, assessment, and individualized supports to improve functioning and life outcomes.

Kansas City hospitals report sharp influenza surge, increasing admissions and illness severity, stressing resources, prompting vaccination campaigns, preparedness efforts, and monitoring to protect vulnerable populations.

Global analysis shows over 27% of adults eligible for GLP-1 obesity therapy, mostly in low-income regions, highlighting access inequities and need for equitable deployment strategies.

Study of pig kidney xenotransplant reveals innate immune activation threatens graft survival, highlights macrophage role, dd-cfDNA monitoring, and need for advanced genetic engineering and immune modulation strategies.

Review highlights advances in thyroid care, supporting laser ablation for benign nodules, exploring metformin benefits, and reassuring safety of radioactive iodine therapy for Graves’ disease.

ICD-11 defines burnout as an occupational phenomenon, supporting workplace screening and organizational interventions alongside clinical care to prevent burnout and promote employee mental health and productivity.

Analysis of 2024 U.S. ballot measures shows mostly protective outcomes for LGBTQ+ health, impacting reproductive, gender-affirming, HIV, and mental health access amid evolving state policies.

Study warns users of GLP-1 weight loss drugs may lack nutritional guidance, risking deficiencies and muscle loss, urging structured dietary support alongside semaglutide and tirzepatide therapy.

Survey shows widespread drug shortages affecting U.S. primary care, harming patient outcomes, altering treatment decisions, increasing administrative burden, and contributing to physician burnout and care disruption.

Qualitative study finds surgeons poorly informed about Maryland’s All-Payer Model, reporting communication gaps, increased care centralization, and limited referral improvements, highlighting need for better clinician engagement.

LesM microfluidic device captures circulating tumor cells by mechanical properties, linking cancer cell biomechanics and intratumoral bacteria to metastasis prediction and personalized antimicrobial treatment strategies.

Anatomical study maps elbow articular nerve branches, revealing musculocutaneous, median, and radial contributions, enabling targeted minimally invasive nerve blockade for improved chronic elbow arthritis pain relief.

UCL study estimates 1.6 million Britons used weight loss drugs, with millions more interested, highlighting rising demand, access inequalities, and concerns about supervision and long-term impacts.

BMJ analysis shows stopping GLP-1 weight loss drugs leads to rapid weight regain and loss of metabolic benefits, underscoring need for long-term lifestyle strategies alongside medication.

Study finds Migrant Protection Protocols exposure increases asylum seeker trauma, violence, and PTSD risk dramatically, challenging policy effectiveness and urging humanitarian, evidence-based immigration reforms globally.

Mayo Clinic’s JAX Shock consortium improves cardiogenic shock outcomes through early identification, coordinated multidisciplinary care, raising survival to 85% and reducing mortality across regional hospitals.

Mayo Clinic study suggests mitral valve surgery offers better durability and survival than TEER in octogenarians with regurgitation, emphasizing individualized decisions based on physiologic age.

Mayo Clinic study shows younger women’s myocardial infarctions often stem from nonatherosclerotic causes like SCAD and embolism, underscoring need for precise diagnosis and tailored treatment.

Study reveals EGPA driven by interferon-mediated inflammation distinct from severe eosinophilic asthma, identifying immune cell signatures and IGF1 pathways as potential therapeutic targets for patients.

Machine learning improves neurocognitive profiling in schizophrenia, enabling precise detection of cognitive deficits, personalized interventions, enhanced diagnostic accuracy, and better patient outcomes in psychiatric care.

Study shows state e-cigarette flavor bans significantly reduce initiation among young adults, but not adolescents, revealing socioeconomic disparities and need for broader, more equitable vaping prevention strategies.

Study finds home-based self-sampling for anal precancer screening cost-effective, boosting access and compliance, especially in high-risk groups, while reducing healthcare costs and improving early detection.

Study reveals racial disparities in persistent chemotherapy-induced alopecia, with Black and Latina breast cancer patients disproportionately affected, highlighting need for counseling and culturally sensitive care.

Meta-analysis shows nature exposure modestly reduces self-reported pain, supporting nonpharmacologic pain management, though heterogeneity and bias highlight need for more rigorous, controlled future studies.

AI-enhanced echocardiography, FDA-approved, detects cardiac amyloidosis with high accuracy, outperforming prior tools and enabling earlier diagnosis and treatment in heart failure patients.

Mayo Clinic study shows mitral valve repair during septal myectomy is safe, durable, and effective for obstructive HCM patients with degenerative mitral regurgitation.

Entropy-informed personalized deep learning improves opioid misuse detection, outperforming traditional models, enabling targeted interventions in pain and addiction care, and addressing the opioid crisis globally.

Vitamin D-rich foods like fatty fish, fortified products, eggs, and tofu support bone and immune health, especially for individuals with limited sun exposure or deficiency risk.

Nearly 25% miss first-trimester prenatal care, increasing risks like preterm birth and low birth weight, highlighting need for improved access, education, and early pregnancy monitoring.

Study identifies FOXQ1-WNT2-β-catenin axis driving triple-negative breast cancer aggressiveness, linking poor prognosis, EMT, invasion, and highlighting miR-96-5p as a promising therapeutic target for future treatment.

TAVR provides minimally invasive aortic stenosis treatment, expanding to patients, guided by multidisciplinary assessment of anatomy, comorbidities, and longevity, while surgery remains appropriate for cases.

Study links neighborhood pollution and socioeconomic disadvantage with genetic risk, increasing psychotic-like experiences in children, underscoring gene–environment interaction and prevention through environmental interventions strategies early.

Winter morning routines boost wellbeing by supporting circadian rhythms, mood, and energy through light exposure, exercise, mindfulness, and nutrition, helping reduce seasonal symptoms and resilience.

Mayo Clinic case series shows CAR-T therapy can be safely used in lymphoma patients with cardiomyopathy or cardiac metastases through careful selection and multidisciplinary cardio-oncology management.

Analysis shows rheumatoid arthritis increases risk of systolic and diastolic heart failure over time, urging integrated cardiology–rheumatology care and proactive cardiovascular monitoring for improved outcomes.

PAD affects millions worldwide, causes limb ischemia, requires multidisciplinary care, early referral, lifestyle changes, and revascularization to prevent amputations, stroke, and heart attack risk reduction.

Catheter ablation in younger AFib patients reduces one-year readmissions without increasing mortality, highlighting benefits but revealing disparities in access by income and race.

Higher PCE cardiovascular risk strongly predicts future AMD, glaucoma, DR, RVO, and HTR, supporting PCE use in primary care for early ocular disease detection.

Study shows many axSpA patients report acceptable symptoms despite high disease activity, highlighting PASS usefulness and need to integrate patient perspectives with clinical measures for better care.

Study shows strong long-term guselkumab persistence in plaque psoriasis, unaffected by BMI or severity, while prior biologic—especially IL-17—use increases discontinuation risk.

Research shows gender- and sexuality-diverse adolescents face much higher depression and anxiety odds, needing targeted mental health support, safer environments, and identity-affirming interventions in Australia.

Study identifies stress and poor sleep worsen psoriasis, while humidity and dust aggravate eczema, guiding tailored management to improve outcomes for patients with inflammatory skin disease.

Study confirms HRV causes adult LRTIs, shows seasonal peaks, co-infections, pneumonia risk in males with fever or cough, emphasizing diagnostic consideration in adult pneumonia cases.

Research shows inattention often misdiagnosed as ADHD, stressing careful evaluation, modest environmental impact, and neurodevelopmental roots to improve diagnostic accuracy and treatment in pediatric practice.

To improve Bacterial Vaginosis outcomes, new research suggests treating male partners. This approach can significantly reduce recurrence rates and enhance the overall standard of care.

Case study reviews management of a 53-year-old with cardiovascular disease and progressive dyspnea, emphasizing thorough evaluation, multidisciplinary care, and critical heart-lung interplay in treatment decisions.

Transcatheter heart valve therapies are rapidly expanding, driven by innovation, broader patient eligibility, rising disease prevalence, competitive dynamics, and need for intervention to improve outcomes.

Choroidal metastasis is the most common intraocular malignancy, often revealing systemic cancer; early ocular detection and modern systemic therapies can improve vision, survival, and outcomes.

Survey finds 45% of U.S. urologists report burnout, limited help-seeking, and licensure mental health questions as key barriers, highlighting urgent need for policy reform.

Study shows 30-day postoperative UTI rates are low at 2.5%, unaffected by antibiotics, with higher risk in younger and female patients, supporting reassessment of postoperative antibiotic use.

Study finds 14% of medical trainees face food insecurity, disproportionately affecting Black and early-year residents, and associated with higher burnout, social isolation, and reduced well-being.

Dedicating appointment time for EHR tasks reduced after-hours work and physician burnout, with minimal productivity impact, suggesting structured EHR time may improve clinician efficiency and well-being.

Gender differences in youth first-episode psychosis affect symptom onset, diagnosis, treatment response, and relapse risk, underscoring the need for gender-sensitive evaluation, earlier detection, and tailored clinical care.

Mayo Clinic highlights imaging, including echocardiography, CT, MRI, and 3D printing, to improve diagnosis, surgical planning, education, and outcomes in adults with congenital heart disease.

Researchers developed MST-AI, an AI model using the Monk Skin Tone scale to significantly improve skin cancer detection accuracy and equity for patients with darker skin.