Less of You: Life on Semaglutide & Tirzepatide
By: Eva Sheie & Kami Gamlem
Language: en
Categories: Health, Fitness, Nutrition, Society, Culture, Personal, Journals
Eva + Kami are two old-ish moms confronting our reasons for being obese while losing weight on semaglutide and tirzepatide, and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast. After a friend (who is a plastic surgeon) talked Eva into starting semaglutide in February of 2023, she lost 70 pounds in 14 months, alternating between long stretches of being stalled at the same weight and consistent but slow weight loss. Chasing a lifelong dream to being considered just overweight and not obese by the BMI calculator, after 14 months Eva switched to tirzepatide to try and reach a goal th...
Episodes
The Dryer Shrunk My Jeans
Jan 09, 2026Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size comments at work.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To help others find great resources for...
I took a 4 week break from semaglutide and here’s what happened
Nov 14, 2025Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years.
Check out Murderland: Crime and Bloodlust in the Time of Serial Killers
Shop Shapermint
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an ema...
You Want Fries With That?
Oct 03, 2025After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too.
New compounded meds including glycine and B12 make a noticeable dent in Eva’s persistent body aches. A 3-week pause in medication to get a tooth pulled has a surprising effect.
We deconstruct our instincts to soften bad news by bribing our children with treats like McDonald’s.
Listen to the new addiction & recovery podcast My Last Relapse
Eva + Kami are two old-ish moms with little kids confronting our reasons for being o...
Replacing one addiction with another?
Sep 05, 2025While working on a project about addiction, Eva realizes she went from drinking and smoking to a food addiction. But she’s not even sure what her “thing” is now, which is… a little terrifying.
Meanwhile, Kami loses some weight—not exactly from a wellness plan, but courtesy of stress and no sleep. Hey, a win’s a win.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We...
I Am Wonder Woman
Aug 29, 2025While wearing a Wonder Woman shirt, Kami heads over to her former workplace to confront her shady former employer after he fails to pay her commission.
Eva’s on a GLP-1 break ahead of a tooth extraction, and gets ready for new head shots for the first time since 2008.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email...
How to hide that you’re on a GLP-1
Aug 15, 2025If you want to keep your meds a secret from someone you live with, here’s how we would keep it secret.
Kami’s cat, Leonardo Von Flouffe, makes his debut.
Eva remembers why she was rejected from the United States Marine Corps (really).
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io...
Have we replaced food noise with mom guilt?
Aug 08, 2025How does being hungry seem to interfere with every activity?
One child can’t stop eating sugar, the other starts yelling about being hungry while sitting in the 4th row at Mary Poppins, and some mom guilt creeps in over kolaches, portion sizes, and generational food baggage.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcast...
The Boss is a Drunk
Jul 25, 2025Kami’s boss’s drinking problem becomes too much. Work drama is affecting her relationship with food too, and she’s trying to reset.
Eva’s prescription changes to a new formula of tirzepatide, B12, and glycine to help with air quotes “muscle fatigue.”
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To he...
Do GLP-1s Help With Binge Eating?
Jul 18, 2025Ashley tried everything. She tried all the diets: Weight Watchers, Nutrisystem, SlimFast, Houston Methodist Medical Weight Management program. Even after a gastric sleeve, her weight climbed back up to 320 lbs.
Going to therapy for binge eating was good, but still didn’t help her lose weight.
In 2024, exhausted from trying to lose weight yet again, she thought, “screw it, if I’m going to be fat, why not just get rid of my double chin?” So she decided to have neck lift surgery and found a plastic surgeon, and that’s where she discovered GLP-1s by acciden...
Not-So Texas Roadhouses
Jun 20, 2025Kami forgets to track her calories and take her meds. Eva sends her daughter to camp and Kami remembers getting left behind at camp at age 12, back when there were no cell phones.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To help others find great resources for GLP-1 medi...
Muffin Top, Sleep Apnea, Payment Plans
May 23, 2025Eva gained a few pounds back and got a muffin top. Kami vs. insurance: It should not be this hard to get sleep apnea treatment.
Yep, you can get a payment plan for weight loss meds. Because results shouldn’t depend on your wallet crying. Learn more about PatientFi!
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email...
No I Don’t Feel Totally Different Now
Apr 25, 2025Kami broke her foot, and can’t move. Eva ate 4 dark chocolate mini eggs and got sick (4 eggs, not 4 bags of eggs). We beat the question “Don’t you feel totally different now?” to death.
Kami
SW 250, CW 198, GW 150?
Eva
SW 280, CW 184, GW 170
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@the...
Teetering on the Edge of One-derland
Mar 14, 2025Kami finally busted through the plateau, now hovering at 200 at officially down 50 lbs. Eva’s creeping toward 100 lbs lost, and had to try on size 8 jeans for the first time since 5th grade.
For the record, yes, we’ve lost weight, but we’re still the same people on the inside. Stop asking if we “feel great.”
We love that we’re inspiring people to take the plunge! Shoutout to @jennpurrr on Instagram for letting us know we’re the reason she started.
See the Nurri protein shakes from Costco
Listen to our episode with...
The GLP-1 and addiction connection no one’s talking about with Dr. Jason Giles
Mar 07, 2025In this special bonus episode, an excerpt from a conversation with Los Angeles Addictionologist Dr. Jason Giles about the potential for GLP-1s as a treatment for substance abuse, explaining their impact on cravings and brain chemistry.
Dr. Giles candidly shares his own journey with addiction, how he overcame it, and how it led him to specialize in addiction medicine.
Learn more about Los Angeles addictionologist Dr. Jason Giles
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves...
Debra’s 6 month progress update & tips for those with only 15 lbs to lose
Feb 14, 2025The Debra returns with a progress update and fills in for Kami, who’s out with the flu.
She started at 168, now at 154, aiming for 150. It took almost two months before the scale even moved, but she stuck with it.
Hear Debra’s thoughtful tips if you’re thinking about using a GLP-1 to lose weight, and why you should be careful who you tell.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. ...
Possibly The Worst Before Photo Ever
Jan 31, 2025Kami stalls at 203 and wonders if it’s time for a higher dose to make it to one-derland.
Eva shares a jaw-dropping “before” pic from August 2021 after eating at Paula Deen’s while in Nashville.
Meet Eva’s doctor, Austin plastic surgeon Dr. Johnny Franco
Kami
SW 250, CW 203, GW 150?
Eva
SW 280, CW 189, GW Just Overweight
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting th...
Tips for Newbies: Getting Started on Semaglutide and Tirzepatide
Jan 03, 2025New to semaglutide or tirzepatide? Here are our tips for what to expect when you are just getting started.
We survived the mountains of Christmas food and Eva let a wardrobe stylist give her closet a full makeover.
Kami
SW 250, CW 205, GW 150?
Eva
SW 280, CW 194, GW 170?
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story...
Even More Rear End Problems
Dec 13, 2024Thanksgiving chaos update, questionable ingredients brought by in-laws, a recurrence of rear-end issues, and how Eva got peer-pressured into tucking in a shirt.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is...
If your weight loss progress is stalled on a GLP-1, here’s my advice
Nov 29, 2024Eva has lost 90 lbs, the equivalent of 9 gallons of paint according to the Lose It! app. It’s Kami’s birthday and she makes big plans for the night. An old friend reaches out at the end of her 2nd month of semaglutide injections with questions about stalled progress.
Kami SW 250, CW 207, GW 150?
Eva SW 280, CW 189, GW 170?
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d l...
No plans to binge
Nov 15, 2024Still blowing money on groceries we end up tossing, planning the menu for Thanksgiving but not planning to binge eat, and excited to have full houses.
Somehow 100 people subscribed to us on YouTube. We don’t know why, but thanks! Here’s where to subscribe if you haven’t already.
Kami
SW 250, CW 211, GW 150?
Eva
SW 280, CW 192, GW 175
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you...
This is Halloween
Nov 08, 2024Eva feels fat and to feel better tries on the largest jeans she ever owned (size 20W).
Kami gives a fire recovery update while wearing a fox costume for Halloween.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To help others find great resources for GLP-1 medical weight loss programs, our new...
Life keeps happening
Nov 01, 2024Kami’s 92-year-old neighbor’s house burns down, the 2nd fire in a year of serving on the HOA board. Eva forgets a full order of groceries in the car on a 90-degree day. Life keeps happening, the only difference is that now we forget to eat.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
It’s just a number, it doesn’t mean anything
Oct 28, 2024Weigh yourself every day. Don’t weigh yourself every day. Only weigh yourself at the weigh-in. Weigh yourself in the morning after you go to the bathroom. Always weigh yourself at the same time every day. Take off your shoes. Don’t wear jeans to the weigh-in. Don’t drink a lot of water on your weigh-in day. Weigh in on Friday so you can cheat on the weekend. Go to your weigh-in in the morning and not the evening. You can eat whatever you want on cheat day. I only ate zero point food all week. I starved myself this w...
Duration: 00:32:01Oat-zempic
Oct 04, 2024Eva's 30 year high school reunion approaches with the same worries as high school, including what to wear and who will I know?
Kami’s in full freak-out mode after watching the Oprah special on AI and hearing about scammers using AI to mimic voices.
Then there’s the whole "Oatzempic" thing blowing up TikTok with oat-based smoothies, which sound disgusting. Kami promises to be brave and try this weird drink so you don’t have to.
Read MedScape’s How 'Oatzempic' Stacks up to Ozempic
Watch Oprah’s AI special
Body dysmorphia, self-injecting B12 & The Debra makes an appearance (Kami’s mom)
Sep 20, 2024Kami’s mom Debra joins with her own skinny shot update after 8 weeks. Kami’s endocrinologist breaks up with her because her thyroid is perfect. Eva worries about a compounded tirzepatide becoming unavailable and attempts to stockpile shots.
The viral cookbook: What to Cook When You Don't Feel Like Cooking by Caroline Chambers
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your sto...
Making weight loss medication affordable in Indiana with Cassie Layne, FNP [BONUS]
Sep 06, 2024Because Cassie Layne, FNP, knows the struggle of dealing with weight firsthand, she’s dedicated to making health and wellness accessible for everyone.
In just over two years, she’s helped over 5,000 people from across all of Indiana reach their weight loss goals with affordable semaglutide for just $98 a month. One of those people is our very own Kami, the co-host of Less of You!
Cassie shares inspiring success stories and clears up common misconceptions about these medications.
Learn more about Monarch Health & Wellness
Follow Cassie on Instagram @monarch_health_wellness
Lea...
The MexiMelt is Coming Back
Aug 30, 2024Taco Bell’s Meximelt is coming back. Eva’s eyesight improves instead of getting worse for the first time since 8th grade. Kami catches a Facebook Marketplace scammer red-handed. Semaglutide combined with Kami’s appetite suppressing ADHD medication is lowering her already low blood pressure.
Kami
SW 250, CW 221, GW 150?
Eva
SW 280, CW 195, GW 170
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to...
Transportation and vacation
Aug 16, 2024Kami’s daughter’s school bus keeps skipping her stop in the morning. She gets a new job but is then un-hired two days later. While on family vacation in Washington, Eva learns the hard way not to eat Red Vines.
Want your own Less of You sticker? DM us on IG @lessofyoupodcast with your mailing address.
Kami
SW 250, CW 222, GW 150?
Eva
SW 280, CW 196, GW 170
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarca...
Quit the medication so you can eat again
Aug 02, 2024Kami’s job as HOA president takes a stressful turn as she fights with State Farm to get construction moved forward on the 4 houses that burned down over a year ago.
Eva self-diagnoses a bizarre new side effect of weight loss by reading Reddit comments, and shares an update on the subpoena from our previous episode.
To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & being updated regularly at lessofyou.com
Kami
SW 250, CW 235, GW 150?
Eva
SW 2...
Insurance coverage, bowel obstruction, stomach paralysis, and SO much more with Dr. Sulagna Misra [BONUS]
Jul 26, 2024After losing more than 70 lbs herself, Dr. Sulagna Misra changed her life and now uses her experience to help others do the same.
Dr. Misra shares her personal weight loss journey, the side effects of GLP-1 she’s experienced personally as well as those her patients have experienced.
Links
Misra Wellness Direct Physician Care in Encino, California
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you co...
More Rear End Problems
Jul 12, 2024Continuing our unintentional rear-end-themed mini series with a fissure while on vacation. Is all the weird stuff we talk about helping anyone? Please tell us if it is.
The murder that made Eva promise to never do nothing again, if you’re curious:
https://www.startribune.com/stephen-allwine-found-guilty-of-killing-his-wife-staging-death-as-suicide/471981953/
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to...
Meet the legend, Dr. Johnny Franco! [BONUS]
Jul 10, 2024Meet the man, the doctor, the legend, who heard about semaglutide and then took it himself, losing over 70 lbs. Realizing his success would help thousands of others change their lives too, he then made semaglutide easily accessible and affordable to his own patients in Austin and San Antonio.
In this clip from the Meet the Doctor podcast, Eva chats with Austin plastic surgeon Dr. Johnny Franco, the doctor who introduced her to the skinny shot.
Listen to the full interview with Austin plastic surgeon Dr. Johnny Franco on Meet the Doctor
Learn more about Dr...
Shit My Pants
Jun 28, 2024After Kami forgot her medication at home (again) and didn’t have medication for 20 days, she invented her own plan for restarting and discovered the consequences.
Eva gets invited to a patient appreciation pool party by a plastic surgeon’s marketing team and now has to decide 1) whether to go and 2) whether to swim at said party.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love t...
Finding One-derland
Jun 14, 2024Kami leaves for a 3+ week trip to Washington and forgets her meds at home and rediscovers the effects of marijuana, while Eva finally reaches the magical place called One-derland and schedules laser treatment to reveal that her legs do still exist and can be exposed to natural light.
Kami
SW 250, CW 225, GW 150?
Eva
SW 280, CW 199, GW 180
A New Drug Switched Off My Appetite. What’s Left?
Wired Magazine
The most exceptional laser specialist anywhere
Jenny Burnley
@Restored by Jenny
Eva + Kami are two old-ish moms with...
Please don’t take my drugs away
May 31, 2024Finally switching to tirzepatide after 4 months of stalled progress, Eva is quickly approaching “one-derland.” Kami learns that the voices in her head are actually just food noise.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight l...
Trying on Swimsuits is Fun?
May 17, 2024Kami fails to prepare for a long trip out of town and runs out of medication. Eva complains about random things like compliments from other people and ponders what might be a side effect.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io.
To learn more about sponsoring this or for details on adver...
My Vacation from the Medication
May 03, 2024Discussing the reactions to photos posted online, getting hit on by a lady valet while parking at SXSW, and whether or not it’s a good idea to take a break from the medication while on vacation so you can eat whatever TF you want.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Follow us on Instagram @lessofyoupodcast
Host: Eva Sheie & Kami Gamlem
Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart
...
My Life Goal Is To Be Just Overweight
Apr 19, 2024In the six weeks since Kami started semaglutide, she’s lost more weight than expected and describes the handful of side effects she’s experienced so far.
Eva complains about the odd phenomenon of people asking “so are you done?” despite still being obese.
Kami - SW 250, CW 235, GW 150?
Eva - SW 280, CW 210, GW Just Overweight
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challe...
Rule #373: Only take photos from 6 feet above
Apr 08, 2024On the mind games of how, when, and who we can take photos with and why… and what inspired (forced) Eva to finally share her previously unseen before and after photos with the world.
And did the circumference of Eva’s head actually get smaller? Is that even possible?
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story on the Skinny Sh...
Chicken Burgers, Dead Birds, and the Aftermath of Kami’s 1st Shot
Mar 25, 2024Five days after Kami’s first semaglutide injection, we catch up on the weirdness of our lives and attempt to figure out why cookies are making Eva feel sick.
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story on Skinny Shot Stories (our other GLP-1 podcast). Get the details at skinnyshotstories.com or send an email to podcasts@theaxis.io.
To lea...
How did we get so fat?
Mar 01, 2024As Kami anxiously awaits the arrival of her first semaglutide shot by mail and what's about to happen, Eva reflects on her eating habits going back to shoplifting candy as a child and binging it while hiding in the Target bathroom.
About Less of You
Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
Are you confronting the same challenges? We’d love to hear your story on the Sk...
Introducing Less of You
Feb 08, 2024While losing weight with the help of semaglutide, Eva Sheie and Kami Gamlem confront our reasons for being obese.
Eva - SW: 280 CW: 213 GW: ?
Kami - SW: 250 CW: 250 GW: ?